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At Zimmer Biomet, we are committed to advancing healthcare through cutting-edge technology and unwavering dedication to improving patient outcomes. Our innovative solutions are designed to meet the evolving needs of the medical community, ensuring efficiency, accuracy, and ultimately, better patient care.

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smHArtfix™

For mild to moderate Osteoarthritis

SmHArtfix contains high molecular weight Sodium Hyaluronate produced by bacterial fermentation, with a PH of 6.8-7.4 intentional for intra-articular use to improve viscosity of synovial fluid. Intended for patients suffering from pain and decreased mobility associated with traumatic or degenerative changes, including osteoarthritis.

The therapy consists of a varying number of injections depending on the medical device:

  • SmHArtfix Multi: three injections, administered weekly

  • SmHArtfix One: one injection

The beneficial effects of the treatment are intended to last for at least six months. Treatment may be repeated, if required.

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Clinical Results
Science Behind smHArtfix

Visco supplementation in Osteoarthritis

  • Improves joint function2

  • Can be clinically effective in pain reduction3,4,5,2

  • Shows more prolonged clinical effects of pain relief after HA intra-articular injection than corticosteroids injections6,7

  • Is associated with delay of TKR surgery in patients with knee osteoarthritis8

Specifications
smHArtfix Multi

3 intra-articular injections, administered at weekly intervals:

  • HA content: 44mg in 2ml (2.2%)

  • Osmolarity: 270-400 mOsm/kg

  • Molecular weight: above 1.2MDa

  • Needle size: 21G

  • Viscosity: 150-380Pa·s

smHArtfix One

Single intra-articular injection:

  • HA content: 120mg in 4.8ml (2.5%)

  • Osmolarity: 270-400mOsm/kg

  • Molecular weight: above 1.5MDa

  • Needle size: 19G

  • Viscosity: 300-650Pa·s

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