For mild to moderate Osteoarthritis
SmHArtfix contains high molecular weight Sodium Hyaluronate produced by bacterial fermentation, with a PH of 6.8-7.4 intentional for intra-articular use to improve viscosity of synovial fluid. Intended for patients suffering from pain and decreased mobility associated with traumatic or degenerative changes, including osteoarthritis.
The therapy consists of a varying number of injections depending on the medical device:
SmHArtfix Multi: three injections, administered weekly
SmHArtfix One: one injection
The beneficial effects of the treatment are intended to last for at least six months. Treatment may be repeated, if required.
Visco supplementation in Osteoarthritis
Improves joint function
Can be clinically effective in pain reduction,,,
Shows more prolonged clinical effects of pain relief after HA intra-articular injection than corticosteroids injections,
Is associated with delay of TKR surgery in patients with knee osteoarthritis
3 intra-articular injections, administered at weekly intervals:
HA content: 44mg in 2ml (2.2%)
Osmolarity: 270-400 mOsm/kg
Molecular weight: above 1.2MDa
Needle size: 21G
Viscosity: 150-380Pa·s
Single intra-articular injection:
HA content: 120mg in 4.8ml (2.5%)
Osmolarity: 270-400mOsm/kg
Molecular weight: above 1.5MDa
Needle size: 19G
Viscosity: 300-650Pa·s
