About UsCareersPatients and CaregiversGeniuZ

Take the conversation further

At Zimmer Biomet, we are committed to advancing healthcare through cutting-edge technology and unwavering dedication to improving patient outcomes. Our innovative solutions are designed to meet the evolving needs of the medical community, ensuring efficiency, accuracy, and ultimately, better patient care.

copyright © 2025 Zimmer Biomet. All Rights Reserved.

PrivacyLegalCookiesUK Modern Slavery Act eLabellingCybersecurityAccessibility SettingsCookies Settings
smHArtfix Header Image

Visco supplementation in Osteoarthritis

  • Improves joint function

  • Can be clinically effective in pain reduction,,,

  • Shows more prolonged clinical effects of pain relief after HA intra-articular injection than corticosteroids injections,

  • Is associated with delay of TKR surgery in patients with knee osteoarthritis

3 intra-articular injections, administered at weekly intervals:

  • HA content: 44mg in 2ml (2.2%)

  • Osmolarity: 270-400 mOsm/kg

  • Molecular weight: above 1.2MDa

  • Needle size: 21G

  • Viscosity: 150-380Pa·s

Single intra-articular injection:

  • HA content: 120mg in 4.8ml (2.5%)

  • Osmolarity: 270-400mOsm/kg

  • Molecular weight: above 1.5MDa

  • Needle size: 19G

  • Viscosity: 300-650Pa·s

Resources

Collateral

smHArtfix™ Flyer
4775.2-EMEA-en

smHArtfix™

smHArtfix Header Image
Home
All Products
smHArtfix™

smHArtfix™

For mild to moderate Osteoarthritis1

SmHArtfix contains high molecular weight Sodium Hyaluronate produced by bacterial fermentation, with a PH of 6.8-7.4 intentional for intra-articular use to improve viscosity of synovial fluid. Intended for patients suffering from pain and decreased mobility associated with traumatic or degenerative changes, including osteoarthritis.

The therapy consists of a varying number of injections depending on the medical device:

  • SmHArtfix Multi: three injections, administered weekly

  • SmHArtfix One: one injection

The beneficial effects of the treatment are intended to last for at least six months. Treatment may be repeated, if required.

Clinical Results
Science Behind smHArtfix
Specifications
smHArtfix Multi
smHArtfix One
6
5
3
7
8
4
2
2

Are you ready for surgery?

Oxford | Main Image (Group)

Oxford® Partial Knee

Explore