- Hip, Knee & Shoulder Arthroplasty 2022 Annual Report. Australian Orthopedic Association National Joint Replacement Registry.
- Annual report 2022. The Swidish Arthroplasty Register.
- Deirmengian, C., et al. Validation of the Alpha Defensin Lateral Flow Test for Periprosthetic Joint Infection. Journal of Bone and Joint Surgery. Nov 5, 2020. DOIi: 10.2106/JBJS.20.00749
- Osman, D. R., et al. Prosthetic Joint Infections. In Cierny III, G. et al. (eds). Orthopedic Knowledge Update. Musculoskeletal Infection. AAOS, 2009.
Intended for Healthcare Professionals
Orthopedic Infection Management
Orthopedic infection is on the rise, and is now the number one reason for revision in primary THA and TKA, as evidenced by data in several orthopedic registers1,2 . Zimmer Biomet is committed to assisting surgeons and infection specialists in defeating orthopedic infection, by offering a full range of products and solutions for their patients covering the 4 pillars of orthopedic infection management – prevention, diagnosis, therapy and re-implantation.
Prevention
Bactiguard Technology is a thin, durable and non-eluting noble metal (gold, silver and palladium alloy coating) that is designed to firmly attach to the implant surface.
When the coating comes into contact with moisture, the noble metals create a unique galvanic (or battery) effect that generates tiny pico currents on the implant surface, designed to reduce bacterial adhesion and subsequent risk of biofilm formation.
To address the growing concerns over antibiotic resistance and to ensure responsible antibiotic stewardship, Bactiguard Technology provides an alternative non-antibiotic-releasing approach to tackle biofilms.
Diagnostics
The first of its kind, the Synovasure Alpha Defensin Lateral Flow Test is specifically designed as an aid for the diagnosis of periprosthetic joint infection (PJI). The test delivers same-day results with speed and accuracy3 .
Therapy
Bacteria can produce Extracellular Polymeric Substance (EPS) to shield themselves from both mechanical and chemical attacks. Bactisure Wound Lavage was specifically designed to remove these structurally resistant forms of bacteria. Our solution is designed to physically deconstruct the protective EPS matrix, making bacteria more susceptible to traditional antibiotics and the body’s normal defense mechanisms.
Re-Implantation
Once an infection has been diagnosed, the gold standard for PJI revision involves a one- or two-stage procedure, which can include debridement, implant removal, placement of antibiotic spacer and re-implantation after extended antibiotic treatment, at least six weeks after the first stage.4 Zimmer Biomet offers a range of hip and knee revision systems designed to meet clinical needs and simplify the complexity of revision THA and TKA.
